Rochester International Airport: where to stay, areas and recommended…

Rochester International Airport is about a 15-minute drive from downtown and the Mayo Clinic campus, with no dedicated public shuttle: you get there by taxi, rideshare or a booked transfer. So rather than the distance from the terminal, choosing a hotel here is mostly about proximity to the clinic. Anyone with early-morning appointments will find it handy to have a hotel linked on foot or via skyway to the Mayo buildings downtown. Those being seen at the Saint Marys campus, further west, are better off in the 16th Street area. Anyone looking for lower prices can choose the southern area toward the airport, with a free shuttle to the clinic.

Downtown and the Mayo Clinic campus

City centre · The airport is about a 15-minute drive away; there is no dedicated public shuttle, so you need a taxi, rideshare or a booked transfer.

Best for: anyone with early-morning appointments who wants to reach the clinic on foot or via skyway

Pros

Direct connection on foot or via skyway/underpass to the Mayo buildings
Downtown restaurants and shops reachable without a car

Cons

Parking is almost always paid
Higher prices during weeks with major medical conferences

Recommended hotels in this area

Kahler Grand Hotel: Connected to the Mayo Clinic by a heated pedestrian underpass, a historic hotel dating from 1921.
Hilton Garden Inn Rochester Downtown: High scores for cleanliness and staff, a few steps from the downtown buildings.

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Saint Marys and 16th Street SW

Neighbourhood · About 15 minutes from the airport; a free local shuttle serves the Saint Marys campus and downtown.

Best for: anyone being seen at the Mayo Clinic's Saint Marys campus, further west of downtown

Pros

Free shuttle dedicated to the Saint Marys campus
Newer hotels, with in-room kitchens for longer stays

Cons

The historic center is not within walking distance
Still need transportation for the main downtown clinic

Recommended hotels in this area

Residence Inn Rochester Mayo Clinic Area: Free shuttle to the Mayo Clinic within 3 miles, suites with kitchen.
Rochester Marriott Mayo Clinic Area: Spacious rooms and breakfast appreciated by guests visiting for extended treatment.

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